Bobbie Jo Stinnett is found strangled to death in her home. Known to be eight months pregnant, paramedics are shocked to find that Bobbie Jo's fetus has been removed through a crude cesarean section. Investigators race to find the newborn.

After David Castor is found dead from poisoning, his wife and stepdaughter are both suspected of crafting the murder plot. The investigation takes an unexpected twist when one suspect attempts to kill the other.

In 1980, Karin Strom is found strangled to death. A seemingly open and shut case turns into a 26-year 'who done it?' DNA taken from three prime suspects is compared to DNA recovered from the victim. The results are startling.

In 2008, 16-year-old Meghan Landowski is found stabbed to death. A seemingly open and shut case turns into a months' long "who done it?" Police methodically eliminate suspects in their hunt for a young girl's killer. The results are shocking.

In 2001, 20-year-old ranger Carrie Nelson is found beaten to death in a park office. The senseless killing turns into a five year long "whodunit?" Investigators turn to science as they track down an elusive and unlikely killer.

For eight years, the Bike Path Killer terrorized women in the Buffalo area - committing seven rapes and two murders. Then, without explanation, the attacks stopped. After a 12-year absence, the Bike Path Rapist resurfaces.

Remains found in a sewer are identified as Tristan Jensen, a 14-year-old boy who was reported missing. Investigators find it hard to believe that another teenager could be the prime suspect in one of the most gruesome murders they have ever seen.

A suburban Oklahoma town is rocked by the stabbing murder of 27-year-old Gary Larson and the rape of his girlfriend. The attacker leaves a trail of bloody footprints in Larson's house. Investigators must follow the footsteps to catch the killer.

25-year-old waitress Corey Parker is found dead in her apartment bedroom with over 100 stab wounds to her body. After two long years of intense investigation, detectives finally zero in on a suspect. But the crafty killer knows he's being watched.

When several prostitutes turn up dead near the Genessee River Rochester police conclude they’re facing a serial killer. Investigators discover that the perpetrator returns to the bodies after the kill. Can they catch him before he strikes again?

Women are disappearing from the streets of Philadelphia. Then Josefina Rivera, a prostitute who’s been missing tells police that she’s been held captive in the basement of a madman. Police descend on the house and make a shocking discovery.

When teenager Lynette Ledford is found naked a strangled to death, Los Angles police determine they’re dealing with two sexually motivated killers. Police then uncover the suspects’ van and find chilling evidence killers’ reign of terror.

New Jersey police investigating a series of mob murders discover the victims are connected to one man, a coldblooded killer named Richard Kuklinski. Can undercover agent Dominick Parlifone infiltrate Kuklinski’s circle and bring him to justice?

Police are shocked when Savannah local Milton Bradley is found brutally murdered. They soon discover he’s the victim of a ruthless killer who preys on gay men. The FBI must track this transient hustler and catch him before he strikes again.

When healthy patients in NJ hospitals die of mysterious causes doctors are baffled. An investigation reveals they were victims of a sinister poisoning spree. Officials hone in on a hospital employee with a questionable record and a troubled past.

Police rush to the home or Raman Salcido, a suspected spree killer whose marriage is crumbling. There they find Ramon’s wife dead and the couple’s three daughters missing. Can police track down Ramon and the girls before it’s too late?