20-year old Bear Diaz has diabetes, leaving him weak and vulnerable. When he vanishes in the night with his TV, backpack and cash, investigators must consider foul play. Then Skylar Tosic disappears, leaving people wondering if the cases are linked.

Kortne Stouffer, 21, vanishes from her bed one night following a couple of scuffles with neighbors and friends. Investigators pursue various leads, but the young beauty is nowhere to be found, and her family clings to an endless hope.

When Macin Smith, 17, doesn't come home from school, his parents worry is he in danger? A note hidden in his wallet leaves his family troubled. And police attempt to piece together the puzzle, while his family vacillates between hope and despair.

A Bible-teaching mom takes a midnight walk and never comes home. But a mysterious note suggests frightening possibilities.

When recent college graduate Jennifer Kesse doesn't show up for work, her friends and family know something is wrong. Their worst fears are realized after her car is found empty and abandoned a mile from her apartment. Police immediately investigate the dozens of construction workers who are building Kesse's apartment complex at that time, however no clear suspect emerges. Almost a decade later, this mysterious case continues to baffle law enforcement and haunt her family.

Former Harlem Globetrotter Rico Harris is driving from LA to Seattle to move in with his fiancée, Jennifer Song. The 37-year old is in constant contact with Song and his mother from the road but, after he mentions a detour into the mountains, all communication ceases.

Brian Histand, a 25-year-old BMX rider, was last seen wandering a field in southern Phoenix. As family and friends search, they learn of Brian's disconcerting behavior in his final days. Have Brian's risky bike moves led to his state of confusion?

60-year-old stonemason, David Riemens, has one final meeting before driving to visit family. He never returns home, and his truck is found abandoned. Desperate to find him, investigators look for clues, but David has vanished into thin air.

37-year-old nurse Tammy Kingery, suffers a mysterious illness and is bed-ridden at home. One day, when her husband and children leave to run errands, they return to discover that Kingery has disappeared. The investigation will reveal dark secrets that lead to all kinds of theories about what happened to Tammy.

When 19-year-old college student Bryce Laspisa heads south to visit his parents in Orange County, CA, what should've been a quick five-hour drive down the freeway turns into a 20-hour expedition. Laspisa is in constant contact with his parents from the road, but he's behaving mysteriously. When his car is found crashed and abandoned in a remote desert park, investigators begin a desperate search for clues into Laspisa’s disappearance.

25-year-old artist Tiffany Daniels is a spontaneous free spirit, but when she doesn't return home from work for days, her brand new roommate grows alarmed. When her car is found abandoned in a beachside parking lot, it’s a desperate race against the clock for any sign of Tiffany.

Jessica Heeringa works the night shift at a gas station to help support her 3-year-old son and fiancé. One evening a customer arrives to find the store empty and the cash drawer left open, investigators find themselves in a race against time to locate the missing 25-year-old mom.

More mysteries are revealed in Kelly's disappearance when video footage of him at a gas station, hours before he disappeared, show him as his normal happy self.

Lauryn Garrett's parents talk about what kind of person she is as well as how her disappearance affected them.

Charli Scott was last seen on a treacherous road, her friends and family fear there's been an accident. But as pieces of evidence surface, the mystery heightens.

Investigator Gary Micco travels with Charli's step-father to check out the site where Chari's burnt out car is located, and all the clues don't seem to be adding up to finding Charli.

In the spring of 2011, 32-year-old Michigan resident Amber Gerweck is busy dividing her time between raising her four children and working full-time. Suddenly her family receives a phone call that leaves them with more questions than answers.

On July 16, 1996, Susan Walsh, a wife, mother and dancer, goes missing after making a phone call outside of her New Jersey home. With a past drug addiction, family and friends are left to wonder if drugs are the reason for her disappearance.

After going through the traumatizing experience of rape, Leah Peebles turns to drugs. Now clean and looking for a fresh start, she moves to Albuquerque, New Mexico where she goes missing three weeks later. Did Leah run away or was she the victim ...

Former Marine, Noah Pippin, is reported missing after failing to appear at drill for the California National Guard in August, 2010. After two months of searching, Noah's parents discover clues that lead them to the Montana forest looking for answers.

Fourteen-year-old Chioma Gray has gotten herself mixed up with a much older boy named Andrew Tafoya. Against her mother's wishes, Chioma keeps seeing him and the inappropriate relationship continues down a harmful path.

In the early hours of May 1st, 2010, Jersey City escort Shannan Gilbert goes missing on the affluent shores of Long Island. Police launch a search through the dense underbrush, and what they find hidden in the weeds will spark a gruesome investig ...

Dana Pastori hoped to leave New Orleans and get custody of her daughters, but she never got the chance. Three years pass and Hurricane Katrina hits before anyone realizes that she is missing. It's not until the flood waters recede that the truth ...

The last time Zebb Quinn was seen, he was leaving his work shift with an acquaintance in Asheville, North Carolina. Family members know the shy teenager’s every move, but they are stunned when the police find his car abandoned.

Bob is a car lover who has found a 1950's model Thunderbird he wants. He announces to his friends that he can afford the car, after his announcement he leaves and isn't seen again.

When 25 year-old college grad, Mitrice Richardson, goes missing after being released from a remote sheriff's station at 12:30 AM, a heated battle for answers ensues. Multiple sightings have family and authorities divided on the young woman's wher ...

Bethany goes missing and police investigate her former roommate, Ronald, to find any leads.

When Hatice goes missing from Toronto and her car is found in New York City, detectives wonder if her fiance is involved. Suspicions are raised when they learn that the man Hatice planned to marry has a trail of missing women behind him.

Satara's drug and criminal record make her unimportant to the police, considering they think that she might have just gone into hiding.

Jesse goes camping in the Superstition Mountains in Arizona in search for gold, but the police have to go searching for him.

The Freeman house is burned down and one body is found in the ashes, but what about the other people who were in the house?

Eighteen Year-Old Jarrod goes missing and the police cannot investigate because they don't suspect any foul play.