20-year old Bear Diaz has diabetes, leaving him weak and vulnerable. When he vanishes in the night with his TV, backpack and cash, investigators must consider foul play. Then Skylar Tosic disappears, leaving people wondering if the cases are linked.

Kortne Stouffer, 21, vanishes from her bed one night following a couple of scuffles with neighbors and friends. Investigators pursue various leads, but the young beauty is nowhere to be found, and her family clings to an endless hope.

When Macin Smith, 17, doesn't come home from school, his parents worry is he in danger? A note hidden in his wallet leaves his family troubled. And police attempt to piece together the puzzle, while his family vacillates between hope and despair.

A Bible-teaching mom takes a midnight walk and never comes home. But a mysterious note suggests frightening possibilities.

When recent college graduate Jennifer Kesse doesn't show up for work, her friends and family know something is wrong. Their worst fears are realized after her car is found empty and abandoned a mile from her apartment. Police immediately investigate the dozens of construction workers who are building Kesse's apartment complex at that time, however no clear suspect emerges. Almost a decade later, this mysterious case continues to baffle law enforcement and haunt her family.

Former Harlem Globetrotter Rico Harris is driving from LA to Seattle to move in with his fiancée, Jennifer Song. The 37-year old is in constant contact with Song and his mother from the road but, after he mentions a detour into the mountains, all communication ceases.

Brian Histand, a 25-year-old BMX rider, was last seen wandering a field in southern Phoenix. As family and friends search, they learn of Brian's disconcerting behavior in his final days. Have Brian's risky bike moves led to his state of confusion?

60-year-old stonemason, David Riemens, has one final meeting before driving to visit family. He never returns home, and his truck is found abandoned. Desperate to find him, investigators look for clues, but David has vanished into thin air.

37-year-old nurse Tammy Kingery, suffers a mysterious illness and is bed-ridden at home. One day, when her husband and children leave to run errands, they return to discover that Kingery has disappeared. The investigation will reveal dark secrets that lead to all kinds of theories about what happened to Tammy.

When 19-year-old college student Bryce Laspisa heads south to visit his parents in Orange County, CA, what should've been a quick five-hour drive down the freeway turns into a 20-hour expedition. Laspisa is in constant contact with his parents from the road, but he's behaving mysteriously. When his car is found crashed and abandoned in a remote desert park, investigators begin a desperate search for clues into Laspisa’s disappearance.

25-year-old artist Tiffany Daniels is a spontaneous free spirit, but when she doesn't return home from work for days, her brand new roommate grows alarmed. When her car is found abandoned in a beachside parking lot, it’s a desperate race against the clock for any sign of Tiffany.

Jessica Heeringa works the night shift at a gas station to help support her 3-year-old son and fiancé. One evening a customer arrives to find the store empty and the cash drawer left open, investigators find themselves in a race against time to locate the missing 25-year-old mom.

More mysteries are revealed in Kelly's disappearance when video footage of him at a gas station, hours before he disappeared, show him as his normal happy self.

Lauryn Garrett's parents talk about what kind of person she is as well as how her disappearance affected them.

Charli Scott was last seen on a treacherous road, her friends and family fear there's been an accident. But as pieces of evidence surface, the mystery heightens.

Investigator Gary Micco travels with Charli's step-father to check out the site where Chari's burnt out car is located, and all the clues don't seem to be adding up to finding Charli.

Bethany goes missing and police investigate her former roommate, Ronald, to find any leads.

Satara's drug and criminal record make her unimportant to the police, considering they think that she might have just gone into hiding.

Jesse goes camping in the Superstition Mountains in Arizona in search for gold, but the police have to go searching for him.

Eighteen Year-Old Jarrod goes missing and the police cannot investigate because they don't suspect any foul play.

The Freeman house is burned down and one body is found in the ashes, but what about the other people who were in the house?

A famous news anchor to the Mason City area has been missing for over three years, investigators are getting frustrated, but have come across a promising tip.

Back country ranger Randy Morgenson was the go to person if someone was lost or missing in Sequoia Kings Canyon National Park, until the day he vanishes. Colleagues search for him in dangerous terrain uncovering unsettling secrets. What happened ...

After four days of searching for a ranger a helicopter is called in. From the air they spot a person -- hopefully this is the missing ranger.

A Nazi commander shoots seven Jews at a concentration camp and gets away with murder. That is, until decades later when an eyewitness comes forward and Rambam launches an manhunt to track a cold-hearted killer who's hiding in plain sight.

Jonathan Green, Rita's attorney, talks about how new laws exist today like the Child Support Enforcement Act to punish the deadbeat dads of the world and how her case contributed to it's development.

Rambam talks about the most absurd situation he's ever found himself out in the field as well as unforeseen acts of nature that have gotten in the way of investigations.

Rambam talks about the one piece of outdated technology that is still useful in investigations today as well as some of the unusual experts he's had to work with on a case.

Jesse, a wanted man, flees to Jerusalem and assumes a new identity while leaving his family behind without money or means to survive.

Steven Rambam hits the streets to do the investigating the police should have done already.

Most birth frauds and romance scams are known as Chiquita Scams.

The Keenan family and John's girlfriend talk about how he was harassed by this one police officer in particular and how it effected his life,