Winston-Salem in 1984 is a city divided by race. And when a young copy editor is raped and stabbed to death blocks from where she worked, the atmosphere is tense. Twenty years pass before Deborah Sykes’ killer finally faces justice once and for all.

Shock waves ripple throughout Clearwater, Florida, when an attractive waitress is found on her bedroom floor stabbed 16 times. As years pass and the case goes cold, police fear DNA might not even find justice for Laura Colannino.

A budding college football player’s life is cut short when his 21st birthday party ends with his murder. A gun shot to the head with a bullet wound so exact that Lexington police think it looks like a hit. But who would want to kill Trent Digiuro?

When Jim Webb, Co-Owner and Head Chef of the General Wayne Inn outside of Philadelphia, is found shot to death in his office, police hatch a plan so risky it could mean letting a killer run free forever.

A murderous attack in Park Slope, Brooklyn, leaves Sylvia Lugo dead and her girlfriend, Amanda Leach, raped and shot in the leg. Police struggle to pin down an assailant without any hard evidence, resulting in Leach being pegged as the prime suspect.

When Wharton business student Shannon Schieber is found raped and strangled to death in her Philadelphia apartment, the city erupts with outrage as it's discovered that Shannon's death is the the latest in a string of rapes in the Centre City area.

When Rachel Kosub is discovered brutally raped, and strangled to death on her office floor, San Antonio police question who could commit such a vicious murder. They struggle to identify a killer until DNA analysis cracks the case, 20 years later.

Terror grips Nashville, TN as employees at popular fast food restaurants are brutally murdered, execution style. Pressure mounts on Nashville Police as the body count rises. Will they ever catch the killer?

Palo Alto’s community sympathize with rich property developer Ken Fitzhugh when his wife of 30 years plus, Kristine, falls to her death down the basement stairs. But police are suspicious from the get go: there is just too much blood at the scene.

Star Washington Redskins safety Sean Taylor is shot dead by an intruder in his Miami home. And when it comes to the rich and famous, it seems like everybody has a motive...

A sultry waitress gets fingered for brutally murdering her husband’s ex-wife. After her brazen prison escape turns the convicted killer into a national celebrity, questions about the case against her come to light.

San Diego police race to catch a killer with an unthinkable calling card.

A body is found engulfed in flames in a Los Angeles alley. He's thought to be the victim of brutal gang violence, but a tip soon leads police to the victim's ex. When new evidence is unearthed years later, it's clear the police were dead wrong.

After he clashes with co-workers, Tom Monfils mysteriously disappears on the job at a Green Bay paper mill. Soon enough it looks like murder, but no one is talking to detectives. Is it a conspiracy of silence, or a tragic miscarriage of justice?

A mother of four goes missing before testifying against her abusive boyfriend.

A young mother from Austin, Texas suddenly drops out of contact. Police believe she may be taking a break somewhere, possibly with a new man. But Julie Ann Gonzalez's family fears the worst.